If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. This included injuries to the soft tissues of the shoulder as well as injuries to bone and joint. Muscle soreness and achy joints are common symptoms among COVID-19 patients. According to the federal Vaccine Adverse Event Reporting System (VAERS) [1], there were 21 deaths this flu season after 180+ million flu vaccines, a rate of 1 death per 9,000,000 vaccinations. * Approximation only. The CDC recommends that you have the COVID-19 vaccine even if you have had an allergic reaction to food, oral medications, pets, or environmental toxins, such as dust or latex, in the past. This may lead to joint pain, eye inflammation, and symptoms that affect various parts of the body. The New York City-based veterinarian said the nurse lodged the shot "extraordinarily high" into her left shoulder, hitting the bursa rather than the deltoid muscle. The symptoms of reactive arthritis usually go away within 35 months. Click here to learn more. Alternatively, arthritis that develops after COVID-19 may be the result of long COVID, or it may be a temporary side effect of the COVID-19 vaccine. National Library of Medicine Tinnitus can develop after any vaccine and tends to happen more often with other vaccines. But during the pandemic, many people's entire workday has been spent at home. The Trump administration recently tried to cut SIRVA from the $4 billion VICP -- which was initially authorized by the National Childhood Vaccine Injury Act of 1986, in response to a rush of lawsuits against vaccine manufacturers -- arguing that it was due to improper administration of vaccines, rather than the vaccine itself. by Original written by Kristin Samuelson. Opens in a new tab or window, Share on Twitter. Can the COVID-19 vaccine cause arthritis? Physical therapy helped improve his range of motion to an extent, but his pain lingers. The report focuses on a 53-year-old man with a family history of RA. The AAOS Patient Safety Committee recommends avoiding musculoskeletal corticosteroid injections for two weeks before and one week after COVID vaccine administration. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. When that table is developed, those who couldn't establish a "Table" injury have a year to file a request for benefits even if their previous request was denied. They can vary across different age groups. "We might see edema and inflammatory changes of the tissues (fluid, swelling), hematomas (collections of blood) or devitalized tissue (gangrene)," Deshmukh said. As the long-awaited COVID-19 vaccine rollout begins across the country and everyone is eager to get back to normal life, it can be confusing to understand what you can and cannot do once you and those around you are vaccinated. The pain largely resolved but returned, albeit to a lesser extent, after 6 weeks, and a follow-up MRI confirmed persistent bursa inflammation. pdf files, Reactivation of IgA vasculitis after COVID-19 vaccination, The Lancet Regional Health Southeast Asia, Statement on offensive historical content. The puncture point should be chosen with the median point of the deltoid muscle or the anterior-posterior axillary line as landmarks because the more cephalad the puncture position, the greater the chance of causing SIRVA. This website also contains material copyrighted by third parties. COVID-19 seems to have the potential to cause pain in a variety of ways, including damage to peripheral nerves causing neuropathy-like symptoms, by affecting pain pathways inside the brain, and by weakening or disrupting the activity of the musculoskeletal system. The COVID-19 vaccine may trigger an RA flare in people who already have the condition, but experts still strongly urge people with the condition to get vaccinated. For instance, a condition called 'shoulder injury related to vaccine administration' (SIRVA) is characterized by shoulder pain and limited range of motion after intramuscular injection of a vaccine into the deltoid muscle of the shoulder. and transmitted securely. However, a 2022 case report notes that some people have developed new or worse symptoms of autoimmune conditions after receiving the COVID-19 vaccine. COVID-19 vaccines produce an antibody reaction that protects you from the disease. pain and swelling in the joints, especially the large joints of the legs, such as the ankles and knees, symptoms that affect only one side of the body, performing strengthening exercises, which prevent muscle wasting. No studies have found a direct link between the vaccine and arthritis. This information is provided as an educational service and is not intended to serve as medical advice. view more . The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Tendonitis. Opens in a new tab or window, Share on LinkedIn. 2 cm deep to the quadriceps tendon and involved the medial and lateral gutter (, Arthrocentesis of the right knee showed 24 mL of inflammatory-appearing effusion (, His rheumatoid arthritis was well controlled before the vaccination, and there were no other inciting events, so we believe that this flare might have been triggered by his immune response to a component of the BNT162b2 vaccine. Stroke in Tamsulosin, how severe and when it was recovered? . It is not intended to provide medical or other professional advice. The U.S. Centers for Disease Control and Prevention (CDC) lists common COVID-19 vaccine side effects as pain, swelling or redness at the injection site; fatigue; headaches; muscle pain; chills;. If you have an acute injurysuch as a sprain or broken bonebut you are not having surgery, there is no reason to delay vaccination. Nausea. What to know about COVID-19 and arthritis. Resurrected Supernova Provides Missing-Link, Bald Eagles Aren't Fledging as Many Chicks, Ultracool Dwarf Binary Stars Break Records, Deflecting Asteroids to Protect Planet Earth, Quantum Chemistry: Molecules Caught Tunneling, Shark from Jurassic Period Highly Evolved. Epub 2021 Oct 1. Some people recover from long COVID in a few weeks, but others do not recover completely. Although the mechanism of flare is not known, one could speculate that one of these components might have had non-specific adjuvant effect, or there could have been molecular mimicry between the viral spike peptides and the patient's self-peptides, activating a flare. Medpage Today is among the federally registered trademarks of MedPage Today, LLC and may not be used by third parties without explicit permission. Subacromial-subdeltoid bursitis following COVID-19 vaccination: a case of shoulder injury related to vaccine administration (SIRVA). If someone believes they may have long COVID, they should make an appointment with a doctor, who can create a medical management plan for them. 2021 Nov;50(11):2293-2297. doi: 10.1007/s00256-021-03803-x. Here, we report a rare case of an 83-year-old woman who was diagnosed with calcification in her left shoulder 1 year ago and developed calcific tendinitis after receiving an mRNA vaccine for COVID-19 (Pfizer-BioNTech). Share this article. However, various side effects have been reported following vaccination. The site is secure. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. "I think it's important to differentiate between what the virus causes directly and what it triggers the body to do," Deshmukh said. I got Covid-19 two months ago. "Everyone ages 18 and older should get a booster shot when they are six months after their initial Pfizer or Moderna series," CDC Director Dr. Rochelle Walensky said in November. KAT authored the paper with edits made by FKT. It's also different from typical post-injection soreness, as the pain is more severe and it can impact mobility and function. Epub 2021 May 4. In such cases, the goal of therapy is to relieve symptoms and prevent long-term complications. Bookshelf Fatigue (feeling of tiredness): 25 people, 13.89%, Mobility Decreased (ability to move is reduced): 17 people, 9.44%, Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 8.89%, Muscle Aches (muscle pain): 15 people, 8.33%, Hypoaesthesia (reduced sense of touch or sensation): 14 people, 7.78%. Other viral infections can do so as well. Sex and gender exist on spectrums. Opens in a new tab or window, Visit us on YouTube. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. "How do you find something if you're unsure of what to look for? Based on this, they concluded that lingering inflammation is the cause. Recap. Symptoms include sudden onset joint pain and swelling, often in multiple joints. Five years later, SIRVA was added to the Vaccine Injury Table, which guides allowable claims in federal vaccine court. "If physical therapy and injection don't work, then primary care refers to us.". The condition is also plagued by the lack of a solid evidence base, and causality is difficult to pin down. Can the Cornonavirus Affect My Bones and Joints? Unable to load your collection due to an error, Unable to load your delegates due to an error. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. 8600 Rockville Pike Can poor sleep impact your weight loss goals? Additionally, the COVID-19 vaccine may cause arthritis-like side effects that can last weeks. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. In females, this can lead to inflammation in the genital and reproductive organs as well. Transformation. Note: Content may be edited for style and length. Radiographs showed calcification of the supraspinatus tendon, and magnetic resonance images showed continuous inflammatory findings from the subdeltoid bursa to the subacromial bursa. "We're certainly not seeing a pandemic of SIRVA" with COVID vaccines, D.J. from the American Academy of Orthopaedic Surgeons, Swelling or redness at the site of the injection, Systemic reactions, such as fever, chills, nausea, vomiting, muscle aches, or fatigue. For weeks, she had severe pain that didn't respond to over-the-counter anti-inflammatory medications. MNT is the registered trade mark of Healthline Media. After adjustment for baseline characteristics, the study found that the hazard of aortic aneurysm increased by 2.24-fold (95% CI=2.02-2.49) during a 30-day risk window following the treatment episode. Gahan, a clinical psychologist in Shrewsbury, United Kingdom, hasn't . Symptoms can vary depending on where the aberrant shot landed, resulting in various manifestations such as bursitis, tendonitis, or adhesive capsulitis (also known as "frozen shoulder"). Is there a link between overactive bladder and COVID-19? Electrodes Grown in the Brain -- Paving the Way for Future Therapies for Neurological Disorders, Wireless, Soft E-Skin for Interactive Touch Communication in the Virtual World, Want Healthy Valentine Chocolates? I'm still discovering new areas of damage -- Richard Quest. Beyond this, the injection is given in the deltoid muscle below the space where bursitis or tendinitis would occur and outside the glenohumeral joint where patients might experience arthritis. Questions and Answers for Patients Regarding Elective Surgery and COVID-19. The Lancet Regional Health Southeast Asia, The Lancet Regional Health Western Pacific, Avoiding diagnostic pitfalls in children with musculoskeletal symptoms, Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis, US Centers for Disease Control and Prevention. The use of the eHealthMe site and its content is at your own risk. doi: 10.12659/MSM.937430. I called the testing center. Two of the vaccines, BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna), are novel mRNA-based vaccines delivered via lipid nanoparticles. That cancer patients delay all imaging for 4 to 6 weeks after the COVID vaccine. There is no evidence that vaccination will interfere with your surgery or recovery. Just a few seconds after the needle penetrated my arm, I felt a mild soreness, kind of like a flu shot. 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Researchers in Italy, for instance, studied 12 people who "reported shoulder stiffness and pain arising after COVID-19, with no apparent cause," according to a paper published in the. It can happen if a person develops reactive arthritis due to the inflammation the infection causes. 18 January 2021. Of the initial COVID-19 claims, the . COVID-19 Vaccines and Allergic Reactions You'll always want to stay at your vaccination site for at least 15 minutes after you get the shot (30 minutes if you've had a severe allergic. Most people witness these side effects after getting the jab which . 20052022 MedPage Today, LLC, a Ziff Davis company. If a radiologist knows COVID can trigger inflammatory arthritis and imaging shows joint inflammation, then they can send a patient to a rheumatologist for evaluation. However, the report does not confirm that this happened. ScienceDaily. The .gov means its official. Like any vaccine, a COVID-19 vaccine may cause pain, swelling, and fever after being administered. Jackson and Noren said SIRVA attorneys advised that their injuries would not likely be compensated under the CICP. Generally, it's characterized as a "constellation of shoulder pain and reduced range of motion that occurs within 48 hours of vaccination and does not resolve within 1 week," according to a recent paper Keeling co-authored. If even after 4-6 months post Covid, you are having persistent pain it needs to be investigated If the patient suffered from autoimmune arthritis then a rheumatologist must be involved While. The reactions can also be. Unauthorized use of these marks is strictly prohibited. Link; Grimm L, et al. Tendonitis is found among people who get Pfizer BioNTech Covid Vaccine, especially for people who are female, 60+ old, and in the first week of getting the vaccine. You can use the study as a second opinion to make health care . COVID-19 is a life threatening condition, and the vaccine is highly protective against the virus SARS-CoV-2, which causes . All rights reserved. They reduce inflammationmarked by swelling, redness, and warmththat is controlled by the immune system. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Normally, taking your shoes off when you get home at the end of the day isn't a big deal. The nasopharyngeal swab was negative for SARS-CoV-2 30 days after the first symptoms. We declare no competing interests. They may be referred out to a specialist such as a physiatrist or an orthopedic surgeon. 'Rest is the most important factor of treating SIRVA - you need to give the muscles, tendons and ligaments time to recover as this problem often causes inflammation. The benefits usually outweigh the risks, as people with RA are more vulnerable to severe COVID-19. Can diet help improve depression symptoms? Bethesda, MD 20894, Web Policies Read on to learn about the possible association between a SARS-CoV-2 infection and joint swelling. Fewer people should get sick, and more lives can be saved. FOIA Will Future Computers Run on Human Brain Cells? Many orthopaedic patients have questions about how the COVID-19 vaccine might impact theirbones and joints. A statement from Johnson & Johnson said that tinnitus was identified as an adverse event in its phase 3 clinical trials of the Covid-19 vaccine but also maintained that it was impossible to. All rights reserved. If you are having a corticosteroid injection for an orthopaedic condition, such as arthritis or carpal tunnel syndrome, your doctor may advise you to wait for a few days after the injection before receiving the COVID-19 vaccine. Treatment for joint pain is available. You can use the study as a second opinion to make health care decisions. Within a few hours of getting her first COVID-19 shot, Leah Jackson had severe pain in her left shoulder. A BIZARRE new side effect has been reported by people who have received their Covid-19 vaccine. Some reports may have incomplete information. References: HRSA Countermeasures Injury Compensation Program: Link or toll-free number 1-855-266-2427 RSA Vaccine Compensation Program Frequently Asked Questions: LInk Cantarelli Rodrigues T, Hidalgo PF, Skaf AY, Serfaty A. Skeletal Radiol. Both programs are administered by the Health Resources and Services Administration (HRSA). (2021, February 18). "One of the most common neurological symptoms in COVID patients, which can still persist after the initial disease, is loss of smell and taste sensation. Reactive arthritis can occur after various infections, even if joint pain was not a symptom during the initial illness. Three COVID-19 vaccines have been approved for emergency use in the USA so far. If you are allergic to polyethylene glycolone of the ingredients used in the COVID-19 vaccinethe CDC advises against being vaccinated. A spokesperson for HRSA confirmed to MedPage Today via email that despite full FDA approval, Pfizer's COVID-19 vaccine (Comirnaty) still remains covered under the CICP and does not yet move to the VICP. Careers. Generally, it's characterized as a "constellation of shoulder pain and reduced range of motion that occurs within 48 hours of vaccination and does not resolve within 1 week," according to a. Keeling and Brent Wiesel, MD, also an orthopedic surgeon at MedStar Georgetown University Hospital in Washington, D.C., recently published an overview of SIRVA in the Journal of the American Association of Orthopaedic Surgeons, stating that it's a "rare yet increasingly recognized complication of immunization.". He or she may also recommend waiting for a period of time after vaccination.Your doctor can answer any questions you may have about the timing of corticosteroid injections and COVID-19 vaccination. Opens in a new tab or window, Visit us on TikTok. MeSH Activities such as typing or texting, golfing, and gardening can worsen these conditions. An official website of the United States government. Copyright 1995-2021 by the American Academy of Orthopaedic Surgeons. 2022 Jul 11;28:e937430. Autoimmunity is when the bodys immune system mistakenly attacks healthy tissue. The former Cowboys' star, who was picked in the first round of the 2015 draft, now claims he can't "run or jump" because of his injuries from playing football. COVID-19 vaccine clinical guidance summary for patients with rheumatic and musculoskeletal diseases. In order to prevent SIRVA, the presence of shoulder joint disease should be carefully asked during a pre-vaccination assessment. Usually appearing up to 48 hours after vaccination, SIRVA is the result of a medical worker administering the vaccine "too high up" on the upper arm. Others can experience an ongoing cough, chest tightness, fatigue,. Dr. Smoking, older age, and preexisting joint pain had links to post-COVID-19 arthritis. Houston, TX - Feb 11, 2021. Epub 2022 Mar 21. These symptoms may last weeks or months. You can learn more about how we ensure our content is accurate and current by reading our. Opens in a new tab or window, Visit us on Twitter. "COVID-19 causes a variety of neurological symptoms, which can stay behind in a patient after initial recovery or can develop later," said Dr. Sanghavi. HHS Vulnerability Disclosure, Help The American Academy of Orthopaedic Surgeons (AAOS) has recently stated that the benefits of the COVID-19 vaccine strongly outweigh the orthopaedic risks. To update your cookie settings, please visit the, https://doi.org/10.1016/S2665-9913(21)00108-9, Flare of rheumatoid arthritis after COVID-19 vaccination, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html, https://www.rheumatology.org/Portals/0/Files/COVID-19-Vaccine-Clinical-Guidance-Rheumatic-Diseases-Summary.pdf, Download .pdf (.2 All data and statistics are based on publicly available data at the time of publication. Anyone seeking specific orthopaedic advice or assistance should consult his or her orthopaedic surgeon, or locate one in your area through the AAOS Find an Orthopaedist program on this website. The body then develops immunity to the spike protein, which protects against the virus. official website and that any information you provide is encrypted Yes, COVID-19 can trigger arthritis in some people. "That imaging allows us to see if COVID-related muscle and joint pain, for example, are not just body aches similar to what we see from the flu -- but something more insidious.". "I just can't move my arm in certain motions," she said. 2022 Apr 20;40(18):2546-2550. doi: 10.1016/j.vaccine.2022.03.037. "It's the patients who have persistent symptoms who are referred to orthopedic surgeons," Keeling said. What is the latest research on the form of cancer Jimmy Carter has? Resting your body may help to. Fever, chills, headache, fatigue, and muscle soreness, are some of the common side effects of getting the COVID-19 vaccination. Send story tips to k.fiore@medpagetoday.com. Surgical treatment options for rotator cuff tendonitis. The tinnitus remains after six weeks with no end in sight. Opens in a new tab or window, Visit us on LinkedIn. Musculoskeletal corticosteroid injections are common procedures which are most often performed in an elective, outpatient setting. 04:20. Opens in a new tab or window, Visit us on Facebook. This is considered an overuse injury caused by repetitive hand or wrist motion. This site needs JavaScript to work properly. Materials provided by Northwestern University. Tendonitis in Johnson & Johnson COVID Vaccine, Abortion spontaneous (naturally occurring miscarriage), Acute myocardial infarction (acute heart attack), Acute upper airway obstruction (blockage occurs in the upper airway), Ageusia (loss of taste functions of the tongue), Agitation (state of anxiety or nervous excitement), Alopecia areata (patchy baldness that typically begins with rapid hair loss), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Angioedema (rapid swelling of the dermis), Appendicitis (inflammation of the appendix), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires), Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system), Arthritis (form of joint disorder that involves inflammation of one or more joints), Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem), Atelectasis (partial or complete collapse of the lung), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue), Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis), Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones), Belching (release of gas from the digestive tract), Blindness transient (sudden loss of vision), Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure), Blood thyroid stimulating hormone decreased, Blood thyroid stimulating hormone increased, Bradycardia (abnormally slow heart action), Breast lump (localized swelling that feels different from the surrounding breast tissue), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Canker sores (painful, open sore in the mouth), Cardiomyopathy (weakening of the heart muscle), Cardio-respiratory arrest (sudden dysfunction of heart and lungs), Cerebral haemorrhage (bleeding within the brain), Cerebral infarction (less blood supply to brain resulting tissue damage), Cerebral thrombosis (blood clot in brain), Chapped lips (cracking, fissuring, and peeling of the skin f lip), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Concussion (short loss of normal brain function in response to a head injury), Coronary artery occlusion (complete obstruction of blood flow in a coronary artery), Coronary heart disease (narrowing or blockage of the coronary arteries), Crohn's disease (condition that causes inflammation of the gastrointestinal tract), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it), Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens), Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Drooling (drop saliva uncontrollably from the mouth), Dyskinesia (abnormality or impairment of voluntary movement), Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear), Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters), Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat), Ejection fraction decreased (systolic heart failure), Encephalopathy (functioning of the brain is affected by some agent or condition), Euphoric mood (excessively happy but may become angry or irritable), Eyelid ptosis (falling of the upper or lower eyelid), Eyelid twitch (spontaneous and uncontrolled spasms of the muscles), Facial paralysis (loss of function of face muscle), Facial paresis (weakness in facial muscle movement), Fainting (loss of consciousness and postural tone), Feeding disorder (when children refuse to eat certain food groups), Fibromyalgia (a long-term condition which causes pain all over the body), Flank pain (a distressing sensation experienced around the lower back and the upper abdomen), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), Gaze palsy (disorders affecting the ability to move both eyes in the same direction), General physical health deterioration (weak health status), Glossodynia (a burning or painful sensation in the tongue), Gout (uric acid crystals building up in the body), Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system), Haematochezia (passage of stools containing blood), Haematoma (collection of blood outside the blood vessels), Hallucinations (sensations that appear real but are created by your mind), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hemiparesis (weakness on one side of the body), Hemiplegia (paralysis of one side of the body), Herpes simplex (herpes simplex is a common viral infection), Hyperacusis (disorder in loudness perception), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hyperthyroidism (over activity of the thyroid gland), Hypervolaemia (abnormally increased volume of blood), Hypoaesthesia (reduced sense of touch or sensation), Hypoaesthesia oral (reduced sense of touch or sensation in mouth), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Idiopathic pulmonary fibrosis (chronic lung disease), Incoherent (talking in a confused and unclear way), Incontinence (lack of moderation or self-control), Injection site erythema (redness at injection site), Injection site haemorrhage (bleeding from injection site), Injection site nodule (small swelling or aggregation of cells in the body, esp.
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